In vitro evaluation of topical gel prepared using natural polymer.
نویسندگان
چکیده
منابع مشابه
In vitro evaluation of topical gel prepared using natural polymer
Department of Pharmaceutical Chemistry, Devsthali Vidyapeeth College of Pharmacy, Rudharpur, Uttrakhand – 263153, India Abstract Nimesulide is a second generation non–steroidal anti–inflammatory agent, which is widely used in the long term therapy of rheumatoid arthritis, in alleviating pain and inflammation. But its short half-life (only 3–4 hr), so its causes more fluctuation. After oral admi...
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Skin delivery of NSAIDs offers several advantages over the oral route associated with potential side effects. In the present investigation, topical gel of meloxicam (MLX) was formulated using N-methyl pyrrolidone (NMP) as a solubilizer and Carbopol Ultrez 10® as a gelling polymer. MLX gel was evaluated with respect to different physicochemical parameters such as pH, viscosity and spreadability....
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ژورنال
عنوان ژورنال: International Journal of Drug Delivery
سال: 2010
ISSN: 0975-0215
DOI: 10.5138/ijdd.2010.0975.0215.02012